Bergacyn® FF is a proprietary botanical complex and contains 50% bergamot albedo fiber, 25% bergamot extract and 25% Cynara cardunculus extract, and is standardized to ≥17% total polyphenols and ≥5% cynaropicrin.
Bergacyn® FF is a proprietary three-component botanical complex containing:
The finished ingredient is standardized to:
It combines the polyphenolic fraction of authentic Calabrian bergamot, the characteristic phytochemicals of wild cardoon and the natural fiber fraction of bergamot.
The FF means “Free Flow.”
It does not mean fiber-free.
Bergacyn® FF contains a substantial bergamot fiber component, with 50% of the formulation consisting of bergamot albedo fiber.
The Free Flow designation distinguishes this formulation within the Bergacyn® platform.
Bergacyn® FF is composed of:
Component | Percentage |
Bergamot albedo fiber | 50% |
Bergamot extract | 25% |
Cynara cardunculus extract | 25% |
Total polyphenols | ≥17% |
Cynaropicrin | ≥5% |
This creates a defined relationship between the concentrated botanical extracts and the bergamot fiber fraction.
Bergacyn® FF uses:
Citrus bergamia Risso et Poiteau
Plant part: Fruit
Cynara cardunculus L.
Plant part: Leaf
The ingredient combines bergamot fruit-derived material with Cynara cardunculus leaf extract.
Bergacyn® FF originates from Calabria, Italy, the historic center of authentic Citrus bergamia cultivation.
This geographic connection brings together two Mediterranean botanical resources:
Calabrian bergamot + Cynara cardunculus.
Bergacyn® FF is standardized to:
≥17% Total Polyphenols
The polyphenolic fraction reflects the concentrated phytochemistry provided principally by the bergamot extract.
≥5% Cynaropicrin
Cynaropicrin is a characteristic sesquiterpene lactone associated with Cynara cardunculus.
The ingredient therefore combines polyphenols, cynaropicrin and bergamot fiber within one formulation.
The bergamot fiber is an integral part of the formulation.
Bergacyn® FF contains 50% bergamot albedo fiber, providing the structural citrus fiber fraction of the bergamot fruit.
This distinguishes Bergacyn® FF from Bergacyn®, which contains a more concentrated combination of bergamot and Cynara cardunculus extracts.
The albedo is the white, spongy inner layer of the citrus fruit located beneath the colored outer peel.
In Bergacyn® FF, the albedo provides the bergamot fiber component of the formulation.
This creates a broader fruit-derived matrix combining bergamot extract with a natural fiber fraction from the bergamot fruit itself.
The three components provide complementary nutritional characteristics.
Bergamot extract provides the concentrated polyphenolic fraction associated with the broader BPF® platform.
Cynara cardunculus contributes cynaropicrin and other characteristic cardoon phytochemicals.
Bergamot albedo contributes the citrus fiber matrix.
Together, they create a botanical complex designed around the interconnected areas of liver health, lipid metabolism, metabolic wellness and cardiometabolic health.
The primary positioning is:
Liver Health + Cardiometabolic Wellness
Bergacyn® FF is particularly relevant to formulations targeting:
Its strongest differentiation is the combination of this composition with published human clinical research.
Yes.
The bergamot-cardoon-fiber formulation has been investigated in published human clinical research examining liver steatosis, body weight and broader cardiometabolic parameters.
This is a key distinction within the Bergacyn® platform: Bergacyn® FF includes the bergamot fiber component used in the clinically investigated formulation.
Published research on the formulation has investigated areas including:
These endpoints reflect the close physiological relationship between liver health and cardiometabolic health.
Yes.
One of the principal published clinical investigations evaluated the combination of bergamot and wild cardoon in subjects with hepatic steatosis.
The study examined changes in liver steatosis alongside metabolic and body-weight parameters.
This makes Bergacyn® FF particularly relevant to formulators developing products around metabolic liver health and healthy liver fat metabolism.
Excess accumulation of fat in the liver is closely interconnected with broader metabolic factors, including:
The liver is therefore not an isolated target.
Supporting healthy liver metabolism can form part of a broader strategy addressing cardiometabolic wellness.
Yes.
The published research was conducted in the context historically described as non-alcoholic fatty liver disease (NAFLD) and hepatic steatosis.
Current medical terminology increasingly uses metabolic dysfunction-associated steatotic liver disease (MASLD).
For dietary-supplement formulation, Bergacyn® FF is particularly relevant to products positioned around healthy liver function, healthy liver fat metabolism and metabolic wellness.
Yes.
Body weight was among the clinically investigated parameters in research involving the bergamot-cardoon formulation.
This is significant because liver fat accumulation and body weight frequently occur within the same broader metabolic environment.
Bergacyn® FF can therefore be considered for metabolic weight-management formulations, particularly where the concept also addresses liver and cardiometabolic health.
Yes.
Research on the bergamot-cardoon combination has also examined vascular and endothelial parameters, extending the scientific rationale beyond liver health alone.
This is consistent with the broader Bergamonte® research platform, in which bergamot polyphenols have been investigated in relation to lipid metabolism, oxidative balance and cardiovascular function.
Yes.
Published research on the bergamot-cardoon combination has examined markers related to oxidative stress and vascular inflammation.
This is relevant because oxidative and inflammatory pathways intersect with liver metabolism, vascular function and cardiometabolic health.
The combination of bergamot polyphenols and Cynara cardunculus therefore provides a broader phytochemical approach than either botanical alone.
A clinical study is most relevant when the commercial formulation closely matches the composition and dose used in the research.
For Bergacyn® FF, the presence of bergamot fiber forms part of the clinically investigated formulation concept.
This allows product developers to work with an ingredient configuration designed around the bergamot + cardoon + bergamot fiber platform used in the published research.
Bergacyn® and Bergacyn® FF are closely related but distinct formulation options.
Bergacyn® | Bergacyn® FF | |
Bergamot extract | 50% | 25% |
Cynara cardunculus extract | 50% | 25% |
Bergamot albedo fiber | — | 50% |
Total polyphenols | ≥34% | ≥17% |
Cynaropicrin | ≥10% | ≥5% |
Core positioning | Liver + cardiometabolic | Liver + cardiometabolic |
Fiber component | No added albedo fiber | Bergamot albedo fiber |
FF | — | Free Flow |
Bergacyn® provides the concentrated extract system, while Bergacyn® FF incorporates the bergamot fiber component.
Yes.
Bergacyn® provides the concentrated bergamot + Cynara cardunculus component, standardized to ≥34% total polyphenols and ≥10% cynaropicrin.
BergaFlow™ provides the bergamot albedo fiber component.
Combining these in the appropriate proportions allows the product developer to create the extract-to-fiber relationship represented by Bergacyn® FF and used in the clinical formulation.
Conceptually:
Bergacyn® + BergaFlow™ → Bergamot Extract + Cynara cardunculus Extract + Bergamot Fiber
This gives formulators flexibility in how they build the clinically relevant bergamot-cardoon-fiber system.
The relationship follows directly from the formulation.
Bergacyn® contains the concentrated extract system at:
≥34% total polyphenols + ≥10% cynaropicrin.
When that extract system represents 50% of the finished formulation and bergamot albedo fiber provides the other 50%, the resulting concentration becomes:
≥17% total polyphenols + ≥5% cynaropicrin.
This is the standardization of Bergacyn® FF.
It provides two formulation routes.
Bergacyn® FF supplies the bergamot-cardoon-fiber system as a complete ingredient.
Alternatively, a developer can work with the more concentrated Bergacyn® and combine it with BergaFlow™ in the appropriate ratio.
This provides formulation flexibility while maintaining the underlying composition associated with the clinical research.
Bergacyn® FF is a multi-component botanical complex rather than a single botanical.
It combines:
This creates a broader formulation approach than conventional single-botanical liver ingredients.
A generic citrus bergamot extract generally consists of an extract of Citrus bergamia alone.
Bergacyn® FF combines three defined components:
Bergamot extract + wild cardoon extract + bergamot albedo fiber.
It is therefore better understood as a clinically researched liver and metabolic-health complex built around bergamot, rather than simply a standardized bergamot extract.
Bergacyn® FF is manufactured from bergamot fruit and Cynara cardunculus leaf and incorporates bergamot albedo fiber as part of the finished formulation.
No enzymes are used during production, and the ingredient is spray dried.
The resulting material is a gold-green powder with an aromatic odor and characteristic bergamot flavor.
Bergacyn® FF is a gold-green powder with an aromatic odor and flavor characteristic of bergamot.
Parameter | Characteristic |
Appearance | Gold-green powder |
pH | 3.0–4.0 |
Mesh size | Passes 60 mesh |
Tapped density | 50–70 g/100 mL |
Moisture | <8.0% |
Water solubility at 40°C | Partial |
As a natural botanical ingredient, some color variation may occur between lots.
Bergacyn® FF is:
These characteristics support its use across a range of nutritional and dietary-supplement applications.
Bergacyn® FF has a three-year shelf life when correctly stored.
It should be kept in a cool, dry environment protected from:
The commercial ingredient is supplied in 20 kg fiber drums.
Bergacyn® FF is available through HP Ingredients as part of the Bergamonte® ingredient portfolio.
Qualified manufacturers, formulators and contract manufacturers can request:
For companies searching for a liver health ingredient, NAFLD supplement ingredient, bergamot for fatty liver, cardiometabolic ingredient, bergamot polyphenols or clinically studied citrus bergamot formulation, Bergacyn® FF provides a defined combination of:
50% bergamot albedo fiber + 25% bergamot extract + 25% Cynara cardunculus extract, standardized to ≥17% total polyphenols and ≥5% cynaropicrin.
