BPF® 30 is a standardized Citrus bergamia Risso extract sourced from Calabria, Italy, delivering 30% combined flavanones and 55% total polyphenols. It is a versatile option for cardiovascular and cardiometabolic formulations.
BPF® 30 provides the characteristic five-flavanone profile of authentic citrus bergamot at a moderate standardized concentration. Derived from the juice and albedo of Citrus bergamia Risso, it combines defined phytochemical composition with formulation flexibility and a scientific heritage centered on lipid, glucose, vascular, and broader cardiometabolic research.
BPF® 30 combines a defined 30% flavanone standardization with human research spanning lipid metabolism, glucose regulation, oxidative vascular markers and endothelial responsiveness. Some studies specifically identify a 30% BPF preparation, while others contribute to the broader BPF® research platform, so each card is presented according to the ingredient preparation and protocol actually evaluated.
In a 30-day study, researchers evaluated 30% BPF at 1,000 mg/day alongside placebo and rosuvastatin groups. The 30% BPF group showed changes across the full lipid profile, with total cholesterol moving from 278 to 191 mg/dL, LDL-C from 191 to 113 mg/dL, HDL-C from 38 to 45 mg/dL, and triglycerides from 238 to 165 mg/dL.
Why it matters: Direct 30% BPF data supports a broad lipid-positioning opportunity across LDL-C, HDL-C, total cholesterol and triglycerides.
The 2013 study also examined markers associated with oxidative vascular stress. Participants receiving BPF showed significant reductions in malondialdehyde (MDA), LOX-1 and phosphoPKB, extending the findings beyond conventional lipid measurements.
Why it matters: The vascular-marker data adds antioxidant and endothelial relevance to BPF® 30 beyond standard cholesterol measurements.
BPF® 30 is standardized so the five principal bergamot flavanones collectively represent 30% of the ingredient. This gives formulators a predictable way to calculate flavanone delivery at different inclusion levels while retaining the characteristic BPF® phytochemical profile.
Why it matters: A 30% active specification makes flavanone delivery easy to calculate against serving size and available formula space.
Research note: Published studies shown in this section include both research specifically identifying a 30% BPF preparation and foundational research conducted on the broader BPF® platform. Findings should be interpreted according to the preparation, dose and protocol used in each study and should not be assumed to establish clinical equivalence across BPF® grades.
Mollace V, Sacco I, Janda E, Malara C, Ventrice D, Colica C, et al. Hypolipemic and hypoglycaemic activity of bergamot polyphenols: From animal models to human studies. Fitoterapia. 2011;82(3):309–316. doi:10.1016/j.fitote.2010.10.014.
Gliozzi M, Walker R, Muscoli S, Vitale C, Gratteri S, Carresi C, et al. Bergamot polyphenolic fraction enhances rosuvastatin-induced effect on LDL-cholesterol, LOX-1 expression and protein kinase B phosphorylation in patients with hyperlipidemia. International Journal of Cardiology. 2013;170:140–145.
BPF® 30 is particularly relevant to formulations that approach cardiovascular and metabolic wellness through multiple interconnected markers. Its strongest scientific heritage is in lipid metabolism, with additional research supporting glucose regulation, vascular function, and antioxidant activity.
BPF® 30 delivers the characteristic BPF® flavanone profile at a moderate concentration, giving developers a defined, research-connected bergamot ingredient. This can be especially useful when serving size, complementary actives, product positioning, and overall formula architecture must be balanced together.
BPF® 30 is positioned as a clinically researched bergamot active for healthy cholesterol and cardiovascular wellness, with glucose metabolism and endothelial function providing meaningful secondary territory. Its direct human research gives brands a substantial story across multiple cardiovascular markers while keeping healthy lipid metabolism at the center.
This makes BPF® 30 particularly relevant to daily heart-health and metabolic formulas that need a recognizable lead benefit with enough clinical breadth to support a more complete product story.
BPF® 30 is a standardized Bergamot Polyphenolic Fraction derived from the juice and albedo of authentic Citrus bergamia Risso. It is standardized to 30% combined principal flavanones and maintains the characteristic five-flavanone BPF® profile.
The five principal flavanones, neoeriocitrin, naringin, neohesperidin, melitidin and brutieridin, collectively represent 30% of the ingredient according to specification. At that standardization, 1,000 mg nominally provides approximately 300 mg of combined flavanones.
Yes. Bergamonte® materials identify 30%-standardized BPF in human research evaluating lipid and glucose parameters at 500 mg/day and 1,000 mg/day, and in a separate 30-day study evaluating 1,000 mg/day across lipid and vascular-related endpoints.
BPF® 30 is primarily suited to capsules, tablets, powder blends, sachets and stick packs. Other formats may be feasible with appropriate development work, particularly around bitterness, solubility or dispersibility, pH and processing conditions.
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