BPF® 30% is a standardized citrus bergamot extract derived from authentic Citrus bergamia Risso grown in Calabria, Italy. It belongs to the Bergamonte® BPF® ingredient platform and is standardized to 30% combined flavanones, including neoeriocitrin, naringin, neohesperidin, melitidin and brutieridin.
BPF® 30% is a standardized bergamot polyphenol fraction derived from the juice and albedo of authentic Citrus bergamia Risso.
It is standardized to 30% combined principal flavanones and retains the characteristic BPF® five-flavanone profile:
The 30% designation refers specifically to the concentration of these combined flavanones, rather than simply to total polyphenols.
This makes BPF® 30% more precisely characterized than a generic citrus bergamot extract specified only by extraction ratio or total-polyphenol content.
The bergamot used for the BPF® platform is sourced from Calabria in Southern Italy, the region most closely associated with commercial cultivation of authentic Citrus bergamia Risso.
Controlled botanical sourcing supports:
The identity of the starting fruit matters because other citrus species marketed broadly as citrus extracts do not necessarily possess the characteristic BPF® flavanone profile.
BPF® 30% is standardized so that the five principal bergamot flavanones collectively represent 30% of the ingredient according to specification.
The five flavanones are:
Neoeriocitrin + Naringin + Neohesperidin + Melitidin + Brutieridin
For example, 1,000 mg of an ingredient standardized to 30% combined flavanones nominally provides approximately 300 mg of combined flavanones, subject to the actual lot specification and assay.
The 30% value therefore describes a defined active fraction rather than a general polyphenol measurement.
BPF® 30% contains the same five principal flavanones that characterize the broader BPF® platform:
These compounds occur naturally in authentic bergamot fruit and juice.
The important point is not merely that five compounds are present, but that the extract maintains the characteristic bergamot flavanone fingerprint rather than being standardized to an unrelated citrus flavonoid or a broad total-polyphenol value.
Melitidin and brutieridin are characteristic bergamot flavanone derivatives and are among the compounds that distinguish authentic Citrus bergamia Risso from many other citrus materials.
They have attracted scientific interest because of their structural characteristics and their relationship to pathways involved in cholesterol metabolism.
Their presence is particularly useful when evaluating the authenticity and phytochemical quality of a bergamot supplement ingredient.
BPF® should nevertheless be understood as a multi-component fraction. Its biological activity cannot be attributed to melitidin and brutieridin alone.
A generic bergamot extract may specify:
BPF® 30%, by contrast, is defined by:
For formulators comparing a bulk bergamot extract, these differences are important because two materials bearing the same common botanical name may not be compositionally equivalent.
No.
Flavanones are one class within the larger polyphenol family.
The 30% specification refers specifically to the combined concentration of the principal BPF® flavanones.
Total polyphenols represent a broader measurement that also includes additional phenolic constituents.
This distinction is important because a supplier describing an extract as “high in polyphenols” has not necessarily demonstrated that the characteristic bergamot flavanones are present at meaningful concentrations.
A technically useful specification should therefore distinguish between:
Total polyphenols
and
Standardized bergamot flavanones.
All four belong to the same BPF® ingredient platform but provide different concentrations of the characteristic flavanone fraction.
Ingredient | Standardized Combined Flavanones | General Position |
BPF® 20% | 20% | Lower-concentration BPF® option |
BPF® 30% | 30% | Moderate flavanone concentration |
BPF® 38% | 38% | Higher-concentration/core clinical BPF® grade |
BPF Gold® | 47% | Highest-concentration BPF® grade |
The appropriate grade depends on the intended daily dosage, active flavanone target, finished dosage form, cost parameters and the particular clinical research being referenced.
Higher standardization is not automatically “better.” It provides more flavanones per gram, which may or may not be necessary for a particular formulation.
BPF® 30% may be appropriate when the objective is to achieve the characteristic BPF® flavanone profile while maintaining greater flexibility in:
BPF® 38% provides greater flavanone density and has particularly strong relevance to the broader BPF® clinical portfolio.
BPF® 30% provides a moderate standardized concentration while remaining part of the same authentic BPF® phytochemical platform.
The decision should therefore be based on the formulation objective, not simply on selecting the largest percentage available.
BPF® 30% is particularly relevant to formulations supporting:
The strongest scientific heritage of the BPF® platform is in lipid and cardiometabolic research.
BPF® 30% is therefore particularly suitable for formulators seeking a standardized bergamot for cholesterol or general cardiovascular-health ingredient rather than a generic botanical extract.
BPF® 30% is supported by the broader body of clinical research conducted on the BPF® platform and by early commercial Bergamonte® material described as standardized to greater than 30% polyphenolic flavonoids. HP Ingredients has historically linked this material to significant improvements in cholesterol parameters in human research.
The landmark 2011 BPF study involved 237 patients with hyperlipidemia, with or without hyperglycemia, who received oral BPF for 30 days. The study reported reductions in total cholesterol, LDL cholesterol and triglycerides, increased HDL cholesterol, and reduced blood glucose.
For scientific accuracy, however, the website should distinguish between:
This prevents the common mistake of treating every bergamot extract or every BPF® concentration as clinically interchangeable.
The landmark publication was:
Mollace V, et al. Hypolipemic and hypoglycaemic activity of bergamot polyphenols: From animal models to human studies. Fitoterapia. 2011;82:309–316.
Study at a Glance
Subjects: 237 adults with hyperlipidemia, with or without hyperglycemia
Duration: 30 days
Ingredient: Bergamot Polyphenolic Fraction (BPF®)
Researchers evaluated:
The study reported significant improvements in lipid parameters and blood glucose following BPF supplementation.
HP Ingredients’ historical description of Bergamonte® reported approximately:
What This Means
This study helped establish the scientific foundation for standardized bergamot polyphenols as a cardiometabolic ingredient.
Limitation
The results should be attributed to the BPF® preparation actually evaluated in the study and should not automatically be generalized to unrelated commercial bergamot extracts.
Published BPF® clinical research has commonly evaluated daily doses in the range of approximately 500–1,000 mg/day, depending on the study population, formulation and endpoint.
A 2019 scientific review concluded that human BPF studies investigating lipid outcomes had commonly used 500–1,000 mg/day for approximately 30–60 days.
For BPF® 30%, the finished-product dosage should be based on:
A formulator should not simply convert a clinical dose used with another BPF® grade based solely on percentage standardization.
The BPF® platform has been studied for its effects on several aspects of lipid metabolism.
Human research has reported improvements in:
Mechanistic research has also investigated pathways associated with cholesterol synthesis and metabolism, including the potential influence of bergamot flavonoids on HMG-CoA-related pathways. Reviews of the clinical literature conclude that oral bergamot preparations have repeatedly demonstrated effects on total cholesterol and LDL cholesterol.
For supplement positioning, the appropriate language is generally support for healthy cholesterol metabolism or maintenance of healthy cholesterol levels, rather than drug-like treatment claims.
The foundational BPF® clinical research also reported a significant reduction in blood glucose among subjects with hyperglycemia.
This is relevant because cholesterol, triglycerides, glucose metabolism and body composition are closely interconnected components of cardiometabolic health.
BPF® 30% may therefore be useful in multi-target metabolic wellness formulations where both lipid and glucose metabolism are part of the product concept.
It should not, however, be presented as a treatment for diabetes or as a replacement for medical therapy.
Yes.
Bergamot is naturally rich in polyphenolic compounds, including flavanones with antioxidant properties. Scientific reviews describe antioxidant and anti-inflammatory activity as important components of the biological profile of bergamot polyphenols.
Oxidative stress is also closely connected with endothelial function, lipid oxidation and cardiometabolic health.
The antioxidant activity of BPF® therefore provides a complementary mechanism to its better-known lipid-metabolism positioning.
Evaluation of BPF® 30% should include more than a total-polyphenol assay.
The quality-control program should confirm:
Chromatographic analysis, including HPLC-based profiling, allows individual flavanones to be distinguished and quantified.
This provides a much stronger basis for authentication than simply reporting a single total-polyphenol percentage.
Yes.
Its moderate flavanone concentration makes BPF® 30% particularly useful in multi-ingredient cardiovascular and metabolic formulations.
Potential complementary ingredient categories include:
Combination design should be based on the intended physiological mechanisms, dosage requirements, finished-product format and regulatory market.
BPF® 30% is primarily suited to conventional nutraceutical formats such as:
Other delivery formats may be technically feasible following appropriate formulation work.
For beverages, gummies and other sensory-sensitive formats, formulators should consider:
HP Ingredients can provide formulation guidance for customers evaluating specific delivery systems.
No.
BPF® 30% is a polyphenol-rich extract derived from the juice/albedo fraction of bergamot, whereas bergamot essential oil is produced primarily from the peel and consists largely of volatile aromatic compounds.
The two materials have different:
A formulator looking for bergamot polyphenols or standardized bergamot flavanones should therefore not substitute bergamot essential oil for BPF®.
At minimum, request:
This allows a formulator to compare bergamot extract suppliers on scientific and technical quality rather than simply cost per kilogram.
BPF® 30% is available through HP Ingredients, working with the Bergamonte®/BPF® ingredient platform developed with Herbal & Antioxidant Derivatives (H&AD) in Calabria, Italy.
Qualified manufacturers and formulators may request, as applicable:
For companies searching for a citrus bergamot extract supplier, bulk bergamot extract, bergamot manufacturer, bergamot supplement ingredient or clinically researched bergamot polyphenol fraction, the key consideration is not simply the percentage printed on the specification.
BPF® 30% combines authentic botanical sourcing, defined flavanone standardization, analytical characterization and the scientific foundation of the Bergamonte® BPF® platform.
