Bergamonte® is a portfolio of standardized Citrus bergamia ingredients and clinically researched formulations developed for product concepts spanning cardiometabolic health, healthy weight, vascular function, liver health, performance and healthy aging.
CHOOSING AN INGREDIENT
The Bergamonte® portfolio includes multiple standardized extracts and specialized ingredient systems rather than a one-size-fits-all bergamot ingredient. Each option has its own composition, scientific positioning, and formulation role, giving product developers greater flexibility when matching an ingredient to a health application, dose, delivery format, and finished-product concept.
clinical health benefits
Bergamonte® has been studied across a broad range of interconnected health applications, extending well beyond its foundational research in cholesterol and cardiovascular wellness. Explore ten areas of scientific interest spanning metabolic health, blood sugar, healthy weight management, endothelial function, cognition, liver health, longevity, and antioxidant support, each supported by research into the pathways and biomarkers that shape overall cardiometabolic health.
Supports cardiovascular wellness by promoting healthy endothelial function, circulation, and cardiometabolic activity.
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Helps maintain a healthy lipid profile by supporting balanced total cholesterol, LDL, HDL, and triglyceride levels already within the normal range.
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Supports healthy glucose metabolism and helps maintain blood sugar levels already within the normal range.
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Supports healthy weight management through pathways involved in appetite signaling, fat metabolism, and cellular energy balance.
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Supports the healthy function of the vascular endothelium to promote normal blood flow, nitric oxide activity, and vascular responsiveness.
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Supports cognitive wellness through research examining executive function, metabolic balance, antioxidant defenses, and cellular health pathways.
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Supports normal liver function through pathways involved in lipid processing, antioxidant defense, cellular renewal, and metabolic health.
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Supports healthy aging by addressing cellular maintenance, metabolic resilience, antioxidant defenses, and cardiovascular wellness.
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Helps strengthen the body’s natural antioxidant defenses against oxidative stress while supporting balanced cellular and inflammatory signaling.
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explore the data
Human studies across the Bergamonte® research platform have examined lipid and glucose metabolism, healthy weight, vascular responsiveness, liver-related measures, antioxidant balance and exercise physiology. Explore the data in the context of the specific ingredient or formulation studied.
Why it matters: One study captured significant changes across glucose and the full lipid profile.
Why it matters: Dedicated human research provides a direct healthy-weight story within the portfolio.
Human research with BPF Gold® in trained cyclists examined nitric oxide availability and endothelial response at rest and after exercise. The study reported significantly higher nitric oxide following supplementation, expanding the clinical platform beyond conventional metabolic markers into vascular physiology.
Why it matters: Direct vascular data extends Bergamonte® beyond the traditional lipid story.
A 12-week randomized, double-blind, placebo-controlled study evaluated a bergamot, wild-cardoon and bergamot-fiber formulation in adults with hepatic steatosis. CAP score decreased approximately 48.2 dB/m versus 26.9 dB/m with placebo, while body weight decreased 4.2 kg versus 2.7 kg.
Why it matters: The study connects liver fat metabolism with broader metabolic and weight outcomes.
Another human study of the bergamot-cardoon platform evaluated antioxidant, oxidative-stress and inflammatory biomarkers. The combined formulation produced the strongest overall response across markers including GPx, MDA and TNF-α, compared with the individual botanical groups and placebo.
Why it matters: Human biomarker research adds antioxidant and inflammatory context to the platform.
Why it matters: One study captured significant changes across glucose and the full lipid profile.
Why it matters: Dedicated human research provides a direct healthy-weight story within the portfolio.
Human research with BPF Gold® in trained cyclists examined nitric oxide availability and endothelial response at rest and after exercise. The study reported significantly higher nitric oxide following supplementation, expanding the clinical platform beyond conventional metabolic markers into vascular physiology.
Why it matters: Direct vascular data extends Bergamonte® beyond the traditional lipid story.
A 12-week randomized, double-blind, placebo-controlled study evaluated a bergamot, wild-cardoon and bergamot-fiber formulation in adults with hepatic steatosis. CAP score decreased approximately 48.2 dB/m versus 26.9 dB/m with placebo, while body weight decreased 4.2 kg versus 2.7 kg.
Why it matters: The study connects liver fat metabolism with broader metabolic and weight outcomes.
Another human study of the bergamot-cardoon platform evaluated antioxidant, oxidative-stress and inflammatory biomarkers. The combined formulation produced the strongest overall response across markers including GPx, MDA and TNF-α, compared with the individual botanical groups and placebo.
Why it matters: Human biomarker research adds antioxidant and inflammatory context to the platform.
FROM SOURCE TO STANDARDIZATION
Bergamonte® begins with authentic Citrus bergamia Risso from Calabria, Italy. Its distinctive polyphenol chemistry is translated through defined extraction and standardization into ingredients designed for reproducible research, differentiated formulation and consistent product development.
What is Citrus
Bergamot?
Citrus bergamia Risso is a distinctive citrus species traditionally grown in Calabria, Italy, and the botanical source behind the Bergamonte® platform.
Why
Calabria, Italy?
Calabria provides the traditional growing environment for authentic Citrus bergamia, making the region central to the fruit’s botanical identity and provenance.
Bergamot vs.
Other Citrus
Citrus bergamia has a distinct phytochemical profile and should not be considered interchangeable with other citrus species such as Citrus aurantium or Citrus medica.
From Fruit to
Ingredient
The juice and albedo of Citrus bergamia provide the botanical material that is processed and standardized into Bergamonte® ingredient formats.
Bergamonte® goes beyond generic antioxidant positioning with standardized polyphenols, defined phytochemistry, analytical characterization, and human oxidative-stress biomarker research.